Model Description

• Extensively used for decades as an all-purpose stock for research and drug safety testing
• Often used as recipient mother in transgenic labs due to its superior nurturing ability
• Swiss Webster females (SW-F) are also ideal pseudopregnant recipients for embryo transfers of black and agouti mouse lines

Origin:

Taconic received the Swiss Webster outbred model from the Rockefeller Institute through Rockland Farms, Inc. in 1940. The mice have been maintained as a closed colony since 1951. The mice were derived by caesarean from randomly chosen breeders and reintroduced into a Barrier Nucleus Expansion Colony in 1965-1969. The mice were derived by caesarean in 1983 from randomly chosen breeders from all Taconic’s barrier units.

Genetics:

Taconic’s outbred colony is known to carry the recessive mutation, Pde6b^rd1

Coat Color Loci:

Tyr^c

Color:

Albino

Species:

Mouse

Animal Diet: NIH #31M Rodent Diet